Cyclin A2 modulates EMT via β-catenin and phospholipase C pathways
نویسندگان
چکیده
منابع مشابه
Cyclin A2 modulates EMT via β-catenin and phospholipase C pathways.
We have previously demonstrated that Cyclin A2 is involved in cytoskeletal dynamics, epithelial-mesenchymal transition (EMT) and metastasis. This phenotype was potentiated by activated oncogenic H-Ras. However, the mechanisms governing EMT in these cells have not yet been elucidated. Here, we dissected the pathways that are responsible for EMT in cells deficient for Cyclin A2. In Cyclin A2-depl...
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ژورنال
عنوان ژورنال: Carcinogenesis
سال: 2015
ISSN: 0143-3334,1460-2180
DOI: 10.1093/carcin/bgv069